Tirzepatide is also started low and stepped up gradually. Here is the standard weekly ladder from the product labels, the spacing between increases, and how brand and compounded schedules can differ. This is commonly-reported information, not a recommendation — your schedule is set by your prescriber.
| Weeks | Once-weekly dose |
|---|---|
| 1–4 | 2.5 mg (starting) |
| 5–8 | 5 mg |
| then +2.5 mg no sooner than every 4 weeks, as needed | 7.5 → 10 → 12.5 → 15 mg (maximum) |
Spacing increases about four weeks apart gives the body time to adjust and keeps side effects milder. Many people stay on a lower maintenance dose rather than climbing to the top — that’s a decision for you and your prescriber.
This is the label’s standard schedule, not a plan we recommend. A compounded product may use a different schedule or concentration.
Drawing from a vial? Turn any milligram step into a syringe mark with the tirzepatide units chart or the free calculator.
Increases are made no sooner than every 4 weeks on the standard schedule, in 2.5 mg steps. A dose can be held longer for tolerability.
The standard maximum is 15 mg once weekly. Your prescriber sets your target, and many people stay on a lower maintenance dose.
Yes — not everyone climbs to 15 mg. Whether to hold at a lower dose is a decision to make with your prescriber.
Not necessarily. Compounded products can follow different schedules and concentrations, so follow your prescriber’s and pharmacy’s plan.
Units depend on your vial’s concentration — use the tirzepatide units chart or the free calculator to convert a milligram dose to a syringe mark.