To work out the units for Sermorelin you need two numbers: how many milligrams (mg) are in your vial, and how many millilitres (mL) of liquid you added to mix it. From those, the math gives you the concentration and then the amount to measure. This page is educational only — it is not medical advice, and it does not recommend a dose. Always follow your prescriber and pharmacist.
Sermorelin is a growth-hormone-releasing hormone (GHRH) analog — a 29-amino-acid fragment that prompts the pituitary to release the body’s own growth hormone rather than supplying growth hormone directly.
Sermorelin was once FDA-approved, under the brand name Geref, for pediatric growth hormone deficiency. The manufacturer voluntarily withdrew it from the market in 2008 for commercial reasons rather than because of a safety finding. There is no FDA-approved sermorelin product in the United States today, so sermorelin prescribed now is compounded by a pharmacy under section 503A or 503B, and a compounded preparation is not an FDA-approved finished drug.
Sermorelin vials are commonly reconstituted with bacteriostatic water — sterile water with a preservative that lets a multi-dose vial be entered more than once. The choice of liquid does not change the units-to-draw math: the calculation depends only on the milligrams in the vial and the millilitres you add. Which diluent to use is a question for your pharmacist; the arithmetic below is the same either way.
The two-step formula is:
(On a standard U-100 insulin syringe, 100 units = 1 mL. Remember that 1 mg = 1000 mcg.)
Example 1 — example only; your vial may differ, confirm with your pharmacist. Suppose a vial holds 5 mg and you add 2 mL of water. Concentration = 5 × 1000 ÷ 2 = 2500 mcg per mL. If someone were measuring a 300 mcg amount purely as arithmetic: 300 ÷ 2500 × 100 = 12 units. This is a neutral illustration of the math, not a recommended dose.
Example 2 — example only; your vial may differ, confirm with your pharmacist. Take the same 5 mg vial but add only 1 mL. Concentration = 5000 mcg per mL, and the same 300 mcg becomes 300 ÷ 5000 × 100 = 6 units. Same powder, same amount — 12 units one way and 6 the other, purely because of the water. That is why you always run your own vial’s numbers.
You will see various Sermorelin amounts quoted online and in supplier literature. They are mentioned here strictly as educational context — they are not a recommendation, and what is appropriate for you is a decision for your physician. Do not take a number from a calculator or a forum. Use this tool only to check the mixing arithmetic for the vial in front of you.
This is a mixing-math and concentration tool, not a dosing tool, and it cannot tell you whether a compound, an amount, or a product is appropriate or safe for you. A few honest reminders:
Pepathary is a free, offline, educational tracker. It does not sell, source, or recommend any product, compound, or dose.
There is no single answer — it depends on the concentration of your mixed vial. For example only: a 5 mg vial mixed with 2 mL of water is 2500 mcg per mL, which would make 300 mcg 12 units; the same vial mixed with 1 mL is 5000 mcg per mL, which would make the same 300 mcg 6 units. Run your own vial's mg and water through the formula, and confirm any amount with your physician — this is mixing math, not a dose recommendation.
That is a question for your pharmacist and for the instructions supplied with your vial — this page does not tell you how much to add. What it does show is how to turn whatever amount you added into a usable number. More liquid makes a more dilute mix (a larger volume per amount), less liquid makes a more concentrated one.
Sermorelin was FDA-approved as Geref for pediatric growth hormone deficiency and was voluntarily withdrawn in 2008 for commercial reasons, not safety. There is no FDA-approved sermorelin product today; what is prescribed now is compounded under 503A or 503B, which is not the same as an FDA-approved product.
No. The calculation depends only on the milligrams in the vial and the millilitres of liquid you add. Whether that liquid is bacteriostatic water, sterile saline or dilute acetic acid, the arithmetic is identical. Which diluent to use is a pharmacist question about solubility and sterility, not a math question.
No. This is a reconstitution (mixing-math) tool that converts your vial mg and liquid mL into a concentration and a measurable amount. It does not recommend, select, or endorse a dose, and the example numbers are neutral illustrations of arithmetic only. Always follow your physician's and pharmacist's instructions.